Cambridge IGF-1 LR3 1000 mcg 99% Purity (UAE)
Cambridge IGF-1 LR3 1000 mcg 99% Purity (UAE) . Human IGF-1 LR3, insulin-like growth factor long arginine 3, protein is a synthetic form of IGF-1 with an N-terminal protein extension that improves potency and metabolic stability. IGF-1 LR3 is often used in the maintenance of human pluripotent stem cells.
Highly pure and bioactive 9 kDa IGR-1 LR3 protein monomer, animal-free (AF) and copyright-protein free (CF).
IGF-1 LR3 activity is determined using the Promega serum response element luciferase reporter assay (*) in transfected MCF-7 cells. EC50 = 12.0 ng/ml (1.3 nM). Buy Cambridge IGF-1 LR3 in Dubai UAE.
Cells are treated in triplicate with a serial dilution of IGF-1 LR3 for 4 hours. Firefly luciferase activity is measured and normalized to the control Renilla luciferase activity. Data from Qk041 lot #104315.
IGF-1 LR3 migrates as a single band at 10 kDa in non-reducing (NR) conditions and upon reduction (R). No contaminating protein bands are visible. Buy Cambridge IGF-1 LR3 in Dubai UAE.
Purified recombinant protein (3 µg) was resolved using 18% w/v SDS-PAGE in reduced (+β-mercaptothanol, R) and non-reduced (NR) conditions and stained with Coomassie Brilliant Blue R250. Data from Qk041 batch #104315. Buy Cambridge IGF-1 LR3 in Dubai UAE.
How does Cambridge IGF-1 LR3 work?
Cambridge IGF-1 LR3 is a synthetic, lengthened analogue of human insulin-like growth factor-1 (IGF-1) designed to mimic and enhance the natural effects of IGF-1 in the body. It differs from native IGF-1 by having an arginine substitution at position 3 and an additional 13 amino acids at its N-terminus, which gives it a longer half-life (about 20-30 hours) and significantly reduces its binding to IGF-binding proteins (IGFBPs). This results in greater potency and prolonged activity compared to regular IGF-1. Buy Cambridge IGF-1 LR3 in Dubai UAE.
IGF-1 LR3 binds to the IGF-1 receptor (IGF1R) on muscle and other cells, activating intracellular signaling pathways such as the PI3K/Akt and RAS/MAPK pathways. These pathways promote cell proliferation, differentiation, protein synthesis, and inhibit apoptosis, leading to increased muscle growth, enhanced fat metabolism, and improved tissue repair. In muscle tissue, it also increases insulin sensitivity, facilitating glucose uptake and reducing fat storage.
Because of its enhanced stability and potency, less IGF-1 LR3 is needed to achieve effects similar to or greater than native IGF-1. It is commonly used in research to study muscle growth, fat metabolism, and regenerative processes. Buy Cambridge IGF-1 LR3 in Dubai UAE.
In summary, Cambridge IGF-1 LR3 works by:
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Binding and activating IGF-1 receptors with higher potency due to reduced IGFBP binding.
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Stimulating muscle cell growth, repair, and protein synthesis via key signaling pathways.
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Enhancing fat metabolism and insulin sensitivity
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Providing prolonged biological activity thanks to its structural modifications. Buy Cambridge IGF-1 LR3 in Dubai UAE.
What are the main benefits of using Cambridge IGF-1 LR3 1000 mcg 99% Purity (UAE)?
The main benefits of using Cambridge IGF-1 LR3 include:
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Enhanced Muscle Growth and Recovery: IGF-1 LR3 stimulates muscle protein synthesis and satellite cell proliferation, promoting lean muscle mass gain and faster repair of muscle tissue after workouts, reducing recovery time. Buy Cambridge IGF-1 LR3 in Dubai UAE.
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Fat Loss and Improved Body Composition: It boosts fat metabolism (lipolysis) while preserving muscle mass, helping reduce body fat percentage and achieve a leaner physique. Buy Cambridge IGF-1 LR3 in Dubai UAE.
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Increased Energy and Athletic Performance: By optimizing glucose uptake and energy use, IGF-1 LR3 enhances stamina, endurance, and strength, supporting more intense and frequent training.
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Anti-Aging and Cellular Regeneration: It promotes tissue repair beyond muscle, including skin, bones, and connective tissue, supporting youthful skin elasticity, bone density, joint health, and overall vitality. Buy Cambridge IGF-1 LR3 in Dubai UAE.
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Improved Metabolic and Cardiovascular Health: IGF-1 LR3 helps regulate glucose metabolism, supports cardiovascular function by improving blood vessel health, and may reduce cholesterol levels.
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Cognitive and Immune Support: It may aid neurogenesis and mood regulation, as well as boost immune cell production and healing processes.
How does IGF-1 LR3 impact fat loss and lean body composition?
IGF-1 LR3 impacts fat loss and lean body composition by promoting fat metabolism while preserving and building lean muscle mass. It enhances lipolysis-the breakdown of stored fat into free fatty acids used for energy-helping reduce overall body fat and particularly targeting visceral fat around organs, which is important for metabolic health. Buy Cambridge IGF-1 LR3 in Dubai UAE.
At the same time, IGF-1 LR3 stimulates muscle protein synthesis and satellite cell proliferation, leading to increased muscle growth (hyperplasia) and reducing muscle breakdown (catabolism). This dual action helps improve body composition by increasing lean muscle mass and decreasing fat percentage, contributing to a more toned and sculpted physique. Buy Cambridge IGF-1 LR3 in Dubai UAE.
Additionally, IGF-1 LR3 improves insulin sensitivity and glucose regulation, optimizing nutrient uptake into muscle cells and supporting efficient energy use, which further aids fat loss and muscle preservation. This metabolic optimization helps maintain a higher metabolic rate, facilitating fat oxidation and preventing fat storage. Buy Cambridge IGF-1 LR3 in Dubai UAE.
In summary, IGF-1 LR3:
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Boosts fat breakdown (lipolysis) and targets visceral fat reduction.
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Preserves and promotes lean muscle growth through enhanced protein synthesis and satellite cell activation.
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Improves insulin sensitivity and nutrient partitioning for better metabolism.
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Supports a leaner body composition by reducing fat mass while increasing muscle mass. Buy Cambridge IGF-1 LR3 in Dubai UAE.
How does IGF-1 LR3 compare to HGH in terms of fat loss?
IGF-1 LR3 and HGH both play important roles in fat loss but differ in their mechanisms and effectiveness:
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HGH (Human Growth Hormone) primarily promotes fat loss by stimulating lipolysis-the breakdown of stored fat into fatty acids used for energy. It increases metabolic rate and fat utilization, making it especially effective for reducing fat when combined with diet and exercise. HGH also indirectly increases IGF-1 production in the liver, which contributes to muscle growth and fat metabolism. Buy Cambridge IGF-1 LR3 in Dubai UAE.
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IGF-1 LR3 works more directly on muscle and other tissues, promoting muscle growth and recovery while supporting fat metabolism. It helps preserve lean muscle mass during fat loss and improves insulin sensitivity, which aids efficient nutrient use and weight management. However, IGF-1 LR3’s fat-burning effects are generally less pronounced than HGH’s lipolytic action. Buy Cambridge IGF-1 LR3 in Dubai UAE.
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Synergistic Effects: Studies show that combining GH and IGF-1 can synergistically increase lean muscle mass and total body weight more effectively than either alone, indicating that their combined use may optimize both fat loss and muscle gain. Buy Cambridge IGF-1 LR3 in Dubai UAE.
HGH tends to have the upper hand in direct fat loss due to its strong lipolytic effects, while IGF-1 LR3 supports fat loss indirectly by preserving muscle and improving metabolism. For best results, they are often used together to maximize fat loss and lean body composition. Buy Cambridge IGF-1 LR3 in Dubai UAE.
Cambridge IGF-1 LR3 1000 mcg 99% Purity (UAE)
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